Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy.

Abstract

Functionalisation of MSN with mannose for PDT applications dramatically improved the efficiency of PDT on breast cancer cells.

• Authors: David Brevet, Magali Gary-Bobo, Laurence Raehm, Sébastien Richeter, Ouahiba Hocine, Kassem Amro, Bernard Loock, Pierre Couleaud, Céline Frochot, Alain Morère, Philippe Maillard, Marcel Garcia, Jean-Olivier Durand
• Journal: Chemical communications (Cambridge, England) (Chem Commun (Camb)) Issue 12 Pg. 1475-7 (Mar 28 2009) ISSN: 1359-7345 [Print] England
• PMID: 19277361 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Lectins, C-Type
• Mannose Receptor
• Mannose-Binding Lectins
• Receptors, Cell Surface
• Silicon Dioxide
• Mannose

Topics

• Apoptosis
• Cell Line, Tumor
• Drug Delivery Systems
• HeLa Cells
• Humans
• Lectins, C-Type (metabolism)
• Mannose (chemistry, metabolism)
• Mannose Receptor
• Mannose-Binding Lectins (metabolism)
• Molecular Structure
• Nanoparticles (chemistry)
• Photochemotherapy
• Receptors, Cell Surface (metabolism)
• Silicon Dioxide (chemistry)