Abstract | BACKGROUND: Corneal nerves can be examined using in vivo confocal microscopy (IVCM). This new technique permits sequential observation of the corneal subbasal nerve plexus and detects early signs of diabetic peripheral neuropathy. OBJECTIVE: DESIGN: Case report. SETTING: RESULTS: Examination of corneal nerves using IVCM at 2 different times during the patient's clinical evolution (peak disease and recovery phase) demonstrated histologic signs that correlated with the results of clinical and electrophysiologic assessments. CONCLUSION: This observation supports the hypothesis that corneal IVCM could also be helpful for the early detection or follow-up of autoimmune peripheral neuropathy.
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Authors | Patrice H Lalive, André Truffert, Michel R Magistris, Théodor Landis, André Dosso |
Journal | Archives of neurology
(Arch Neurol)
Vol. 66
Issue 3
Pg. 403-5
(Mar 2009)
ISSN: 1538-3687 [Electronic] United States |
PMID | 19273761
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Immunologic Factors
- Myelin-Associated Glycoprotein
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Topics |
- Autonomic Nervous System Diseases
(diagnosis, drug therapy, immunology)
- Cornea
(innervation, pathology)
- Humans
- Immunologic Factors
(therapeutic use)
- Male
- Microscopy, Confocal
(methods)
- Middle Aged
- Myelin-Associated Glycoprotein
(immunology)
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