Abstract | OBJECTIVE: DESIGN AND SUBJECTS: RESULTS: Glycaemia was well controlled in both groups (mean HbA1c 6.99+/-0.81% in APS-2 patients versus 6.69+/-1.03% in control patients). The mean weight-adjusted daily dose of insulin was non-significantly higher in patients with APS-2 compared with control patients (0.69+/-0.35 IU/kg body weight versus 0.51+/-0.17 respectively). The mean insulin (IU)/ carbohydrate-ratio for 10 g of carbohydrate in the morning was 1.9+/-1.0 and 1.4+/-0.5 respectively. However, the insulin/ carbohydrate-ratios were significantly higher in the APS-2 patients both at noon (mean ratio 2.0+/-0.9 vs 1.1+/-0.5 in control patients) and in the evening (mean ratio 2.1+/-1.1 vs 1.3+/-0.5 respectively; P<0.05). CONCLUSIONS:
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Authors | Ulf Elbelt, Stefanie Hahner, Bruno Allolio |
Journal | European journal of endocrinology
(Eur J Endocrinol)
Vol. 160
Issue 6
Pg. 919-24
(Jun 2009)
ISSN: 1479-683X [Electronic] England |
PMID | 19273569
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Addison Disease
(drug therapy, pathology)
- Adult
- Aged
- Diabetes Mellitus, Type 1
(complications, drug therapy, pathology)
- Female
- Glucocorticoids
(deficiency, therapeutic use)
- Hormone Replacement Therapy
(methods)
- Humans
- Hypoglycemia
(etiology)
- Insulin
(administration & dosage, therapeutic use)
- Middle Aged
- Polyendocrinopathies, Autoimmune
(complications, drug therapy)
- Retrospective Studies
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