Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report.

Abstract

PURPOSE:

To report topography-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) after penetrating keratoplasty for keratoconus.

METHODS:

A 34-year-old woman with irregular astigmatism after penetrating keratoplasty in the right eye underwent PRK. Topography-guided surface ablation using the customized aspheric treatment zone ablation (CATz) was programmed for a 5.00-mm optical zone and an 8.50-mm transition zone. Mitomycin C was applied to corneal stroma for 20 seconds immediately after excimer laser ablation.

RESULTS:

Two months after surgery, the patient was very satisfied with the refractive outcome. Best spectacle-corrected visual acuity was 20/20 with a manifest refraction of -0.50 diopters. No haze formation was detected at 6-month follow-up. A significant improvement in the central 3 mm of the axial topography was noted.

CONCLUSIONS:

Topography-guided ablation using MMC may be a reasonable alternative for the management of refractive error after penetrating keratoplasty.

• Authors: Jackson Barreto Jr, Marcelo V Netto, Alexandre Reis, Mayumi Nakano, Milton Ruiz Alves, Samir Jacob Bechara
• Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) (J Refract Surg) Vol. 25 Issue 1 Suppl Pg. S131-5 (01 2009) ISSN: 1081-597X [Print] United States
• PMID: 19248542 (Publication Type: Case Reports, Journal Article)

Chemical References

• Alkylating Agents
• Mitomycin

Topics

• Adult
• Alkylating Agents (administration & dosage)
• Astigmatism (drug therapy, etiology, surgery, therapy)
• Combined Modality Therapy
• Corneal Topography
• Female
• Humans
• Keratoconus (surgery)
• Keratoplasty, Penetrating (adverse effects)
• Lasers, Excimer (therapeutic use)
• Mitomycin (administration & dosage)
• Myopia (drug therapy, etiology, surgery, therapy)
• Photorefractive Keratectomy
• Visual Acuity (physiology)