HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Hemicraniectomy for massive middle cerebral artery infarction: a review.

Abstract
Hemicraniectomy and opening underlying dura mater permits the expansion of infarcted, swollen brain outwards, reversing dangerous intracranial pressure elevations and the risk of fatal transtentorial temporal lobe or diencephalic herniation. Recently published randomized controlled trials have proven this procedure a powerful life-saving measure in the setting of malignant middle cerebral artery infarction and allayed concerns that a reduction in mortality is accompanied by an unacceptable increase in patients suffering severe neurological impairments. Appropriate patients are relatively young, in the first five decades of life, suffering infarction of a majority of the middle cerebral artery (MCA) territory in either hemisphere, and decompression should be performed prior to progression to coma or two dilated, fixed pupils. Lethargy combined with midline shift and uncal herniation on neuroimaging is an appropriate trigger to consider and discuss surgical intervention. Families and, when possible, patients themselves, should be informed of the certainty of at least moderate to mild permanent deficits, and the possibility of worse. To be successful decompression must be extensive, targeting a bone flap measuring 14 cm from front to back, and extending 1 to 2 cm lateral to the midline sagittal suture to the floor of the middle cranial fossa at the level of the coronal suture. An augmentation duraplasty is mandatory.
AuthorsDulka Manawadu, Ahmed Quateen, J Max Findlay
JournalThe Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (Can J Neurol Sci) Vol. 35 Issue 5 Pg. 544-50 (Nov 2008) ISSN: 0317-1671 [Print] England
PMID19235437 (Publication Type: Journal Article, Review)
Topics
  • Brain Edema (etiology, physiopathology, surgery)
  • Craniotomy (methods, standards, statistics & numerical data)
  • Emergency Medical Services (methods, standards, statistics & numerical data)
  • Hernia (etiology, prevention & control)
  • Herniorrhaphy
  • Humans
  • Infarction, Middle Cerebral Artery (complications)
  • Intracranial Hypertension (etiology, physiopathology, surgery)
  • Patient Selection
  • Plastic Surgery Procedures (methods, standards)
  • Risk Assessment
  • Skull (anatomy & histology, surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: