Abstract | BACKGROUND: Induced hypotensive anesthesia is a well established technique in adult patients. We examined retrospectively the effect of sodium nitroprusside pediatric patients undergoing pelvic osteotomy with simultaneous femoral osteotomy. METHODS: Twenty-three patients received sodium nitroprusside-induced hypotensive anesthesia (group N) and 14 patients received standard anesthesia (group C). In patients of Group N, a target mean arterial blood pressure of 50-60 mmHg was achieved by intravenous administration of sodium nitroprusside. RESULTS: Significant differences were observed between the two groups in the amounts of intra-operative blood loss and fluid infusion. Group N had less intra-operative blood loss than Group C (Group N: 7.3 +/- 4.1 ml x kg(-1) vs. Group C: 10.9 +/- 4.0 ml x kg(-1), P<0.05). Group N had less intra-operative fluid infusion than Group C (Group N: 37.7 +/- 11.2 ml x kg(-1) vs. Group C: 53.9 +/- 15.0 ml x kg(-1), P<0.05). Urine output was not significantly different (Group N: 6.0 +/- 6.2 ml x kg(-1) vs. Group C: 7.0 +/- 5.7 ml x kg(-1), P=0.60). There were no side effects of sodium nitroprusside-induced hypotension. CONCLUSIONS: These results suggest that sodium nitroprusside is a safe and effective drug for induced hypotension in pediatric patients.
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Authors | Satoshi Toyama, Chinobu Okada, Naoki Ikeda |
Journal | Masui. The Japanese journal of anesthesiology
(Masui)
Vol. 58
Issue 2
Pg. 174-7
(Feb 2009)
ISSN: 0021-4892 [Print] Japan |
PMID | 19227170
(Publication Type: English Abstract, Journal Article)
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Chemical References |
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Topics |
- Blood Loss, Surgical
- Child
- Female
- Humans
- Hypotension, Controlled
(methods)
- Male
- Nitroprusside
(administration & dosage)
- Osteotomy
- Retrospective Studies
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