[Do results of the recent clinical trials change the place of valproate in treatment of epilepsy?].

Abstract

Valproate is one of the most extensively used antiepileptic drugs with a broad spectrum of efficacy and a relatively good tolerance. Results of two recently performed clinical trials (SANAD, VIP-e) indicate that valproate should remain first-line treatment in most patients with generalized seizures, and for its high efficacy valproate should be also considered as first-line therapy in patients with focal onset seizures.

• Authors: Magdalena Bosak
• Journal: Przeglad lekarski (Przegl Lek) Vol. 65 Issue 11 Pg. 807-9 ( 2008) ISSN: 0033-2240 [Print] Poland
• Vernacular Title: Czy wyniki nowych badań wpłynA na miejsce walproinianów w terapii padaczki?
• PMID: 19205366 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Anticonvulsants
• Valproic Acid

Topics

• Anticonvulsants (therapeutic use)
• Clinical Trials as Topic
• Epilepsy (drug therapy)
• Humans
• Seizures (drug therapy)
• Valproic Acid (therapeutic use)