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Mycobacterium tuberculosis-specific immunospot assay of pleural exudate mononuclear cells is useful for the exclusion of tuberculous pleuritis in patients with lupus pleuritis.

Abstract
It is often difficult to make a diagnosis of pleuritis associated with rheumatic diseases because of lack of specific diagnostic tools. We report a patient with lupus pleuritis from which tuberculous pleuritis was distinguished by Mycobacterium tuberculosis-specific enzyme-linked immunospot assay of pleural exudate mononuclear cells. After the diagnosis of lupus pleuritis, the patient was successfully treated with prednisolone.
AuthorsK Takase, S Ohno, H Ideguchi, S Murakami, M Takeno, Y Ishigatsubo
JournalLupus (Lupus) Vol. 18 Issue 2 Pg. 175-7 (Feb 2009) ISSN: 0961-2033 [Print] England
PMID19151122 (Publication Type: Case Reports, Journal Article)
Topics
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Lupus Erythematosus, Systemic (complications)
  • Middle Aged
  • Pleural Effusion (immunology)
  • Pleurisy (diagnosis, immunology)
  • Tuberculosis, Pleural (diagnosis)

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