Abstract | PURPOSE: METHODS: RESULTS: CONCLUSIONS: By demonstrating the presence of the 2D03 epitope in human atherosclerotic lesions our findings support the possibility that treatment with this antibody may have beneficial effects also in humans. Furthermore, they suggest the possibility to use these or other similar antibodies for diagnostic imaging of atherosclerotic plaques in humans.
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Authors | Isabel Gonçalves, Mihaela Nitulescu, Mikko P S Ares, Gunilla Nordin Fredrikson, Bo Jansson, Zhan-Chun Li, Jan Nilsson |
Journal | Atherosclerosis
(Atherosclerosis)
Vol. 205
Issue 1
Pg. 96-100
(Jul 2009)
ISSN: 1879-1484 [Electronic] Ireland |
PMID | 19150065
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Apolipoprotein B-100
- Epitopes
- Immunoglobulin G
- Recombinant Proteins
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Topics |
- Aged
- Animals
- Apolipoprotein B-100
(immunology)
- Atherosclerosis
(immunology, metabolism, therapy)
- Carotid Arteries
(pathology)
- Epitopes
(chemistry)
- Female
- Humans
- Hypercholesterolemia
(immunology, metabolism)
- Immunoglobulin G
(chemistry)
- Male
- Mice
- Middle Aged
- Recombinant Proteins
(chemistry)
- Ultrasonography
(methods)
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