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Upper-extremity deep vein thrombosis in a patient on clozapine therapy carrying the prothrombin G20210A mutation.

Abstract
Clozapine treatment for resistant schizophrenic disorders has been associated to venous thromboembolic events. We report the case of a patient who developed upper-extremity deep vein thrombosis just 2 months after starting on clozapine in whom the thrombophilia work-up revealed the presence of the prothrombin G20210A mutation.
AuthorsAmparo Vayá, Maria Lopez, Gema Plumé, José Ribes
JournalPathophysiology of haemostasis and thrombosis (Pathophysiol Haemost Thromb) Vol. 36 Issue 2 Pg. 105-7 ( 2008) ISSN: 1424-8840 [Electronic] Switzerland
PMID19127092 (Publication Type: Journal Article)
CopyrightCopyright 2009 S. Karger AG, Basel.
Chemical References
  • Prothrombin
  • Clozapine
Topics
  • Clozapine (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Point Mutation
  • Prothrombin (genetics)
  • Thrombophilia (genetics)
  • Upper Extremity
  • Venous Thrombosis (drug therapy, genetics)

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