Abstract | OBJECTIVES: METHODS: Case report. RESULTS: A 21-year-old woman who wore soft contact lenses for management of keratoconus presented with a painful suppurative corneal infiltrate and epithelial defect. The patient was initially seen in an emergency department where she was given a bottle of topical anesthetic drops ( proparacaine) to use for pain. When she was seen by the authors 18 hr after presenting to the emergency department, the proparacaine was immediately discontinued, and she was treated with fortified antibiotic ( vancomycin and tobramycin) eye drops and oral antiviral medications ( famciclovir). Despite an initial improvement and complete resolution of ocular discomfort, the patient went on to develop a dense, peripheral stromal infiltrate that failed to improve despite intensive treatment. Confocal microscopy and corneal biopsy were definitive for acanthamoeba infection. The patient subsequently failed medical therapy and underwent large diameter penetrating keratoplasty. The patient has shown no evidence of acanthamoeba recurrence in the corneal graft. CONCLUSIONS:
|
Authors | Eric Jay Wolf, Kenneth Joel Wolf, Lynda Z Kleiman |
Journal | Eye & contact lens
(Eye Contact Lens)
Vol. 35
Issue 1
Pg. 38-40
(Jan 2009)
ISSN: 1542-233X [Electronic] United States |
PMID | 19125047
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Anesthetics, Local
- proxymetacaine
- Propoxycaine
|
Topics |
- Acanthamoeba Keratitis
(complications, diagnosis, surgery)
- Anesthetics, Local
(administration & dosage, adverse effects)
- Contact Lenses, Hydrophilic
- Cornea
(pathology)
- Drug Administration Schedule
- Female
- Humans
- Keratoconus
(complications, therapy)
- Keratoplasty, Penetrating
- Microscopy, Confocal
- Propoxycaine
(administration & dosage, adverse effects)
- Young Adult
|