Abstract | OBJECT:
Hyperbaric oxygen therapy (HBO) is used as primary and/or adjunctive therapy in the treatment of various clinical conditions complicated by local hypoxia. It may have therapeutic potential in the treatment of neurosurgical infections such as spinal osteomyelitis that are associated with significant morbidity rates. The purpose of this study was to evaluate the efficacy of HBO therapy in the treatment of spinal osteomyelitis. METHODS: The clinical records of patients diagnosed with spinal osteomyelitis who received HBO therapy during their treatment at the authors' institution over the past 10 years were retrospectively reviewed. Six adult patients were identified. Four patients had recently undergone spinal surgery and secondary spinal osteomyelitis had developed. These patients received adjunctive HBO therapy due to significant comorbidities and risk factors for poor healing. RESULTS: All patients remained symptom and infection free over the subsequent follow-up period. Two patients had primary spinal osteomyelitis that had recurred despite a full course of appropriate antimicrobial therapy. Infection control was achieved after HBO therapy in 1 patient. The mean follow-up period for the study group was 2.9 years (range 5 months to 5 years). CONCLUSIONS:
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Authors | Raheel Ahmed, Meryl A Severson, Vincent C Traynelis |
Journal | Journal of neurosurgery. Spine
(J Neurosurg Spine)
Vol. 10
Issue 1
Pg. 16-20
(Jan 2009)
ISSN: 1547-5654 [Print] United States |
PMID | 19119927
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Comorbidity
- Female
- Follow-Up Studies
- Humans
- Hyperbaric Oxygenation
(adverse effects, statistics & numerical data)
- Male
- Middle Aged
- Osteomyelitis
(epidemiology, therapy)
- Retrospective Studies
- Risk Factors
- Spinal Diseases
(epidemiology, microbiology, therapy)
- Staphylococcal Infections
(epidemiology, therapy)
- Treatment Outcome
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