Abstract |
Most studies show a trend toward a beneficial or at least neutral effect of associating corticosteroids and antibiotics. However, caution must be taken, with various factors considered: the type, virulence, and size of the inoculum, and the treatment chosen. Early intravitreal administration of 400 microg of dexamethasone seems to be beneficial in treating postoperative Staphylococcus epidermidis-related endophthalmitis. However, a large-scale prospective, randomized, controlled study is mandatory to gain evidence supporting steroid therapy in postoperative endophthalmitis.
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Authors | M Saleh, F Jehl, G Prevost, C Speeg-Schatz, T Bourcier |
Journal | Journal francais d'ophtalmologie
(J Fr Ophtalmol)
Vol. 31
Issue 8
Pg. 825-33
(Oct 2008)
ISSN: 1773-0597 [Electronic] France |
Vernacular Title | Intérêt des corticoïdes dans la prise en charge de l'endophtalmie postopératoire aiguë bactérienne. |
PMID | 19107051
(Publication Type: English Abstract, Journal Article, Review)
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Chemical References |
- Adrenal Cortex Hormones
- Anti-Bacterial Agents
- Anti-Inflammatory Agents
- Cytokines
|
Topics |
- Adrenal Cortex Hormones
(administration & dosage, therapeutic use)
- Animals
- Anti-Bacterial Agents
(administration & dosage, therapeutic use)
- Anti-Inflammatory Agents
(administration & dosage, therapeutic use)
- Combined Modality Therapy
- Cytokines
(physiology)
- Drug Evaluation, Preclinical
- Drug Therapy, Combination
- Endophthalmitis
(drug therapy, etiology, surgery)
- Humans
- Injections
- Mice
- Models, Biological
- Postoperative Complications
(drug therapy, etiology)
- Prospective Studies
- Randomized Controlled Trials as Topic
(statistics & numerical data)
- Retinal Detachment
(etiology, prevention & control)
- Staphylococcal Infections
(drug therapy, etiology)
- Vitrectomy
(methods)
- Vitreous Body
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