A 31-year-old woman suffering from stomach
pain was admitted to our hospital, and diagnosed with unresectable advanced
gastric cancer. She was initially treated with combination
therapy of S-1 and CDDP, and a partial response was achieved. After two courses of the
chemotherapy, however, she complained of
dyspnea, and pulmonary carcinomatous
lymphangitis was confirmed by computed tomography. As second-line chemo-
therapy, we attempted combination
therapy with
docetaxel, CDDP and S-1(DCS). After one course of the combination
therapy, a remarkable response in the pulmonary carcinomatous
lymphangitis was achieved. Treatment of patients with advanced
gastric cancer associated with pulmonary carcinomatous
lymphangitis is quite difficult and there is no scientific evidence to select anti-
cancer drugs for these patients. We concluded that DCF could be a useful regimen for patients with
gastric cancer associated with pulmonary carcinomatous
lymphangitis.