Abstract |
Inhibin B is a gonadal dimeric peptide, produced in men in testicular Sertolli cells. Inhibin B blood level knowledge can be a useful tool in the management of difficult diagnostic problems, such as ambiguous genitalia, the distinction between cryptorchidism and anorchidism and the hypogonadotrophic hypogonadism/ delayed puberty differential diagnosis. Inhibin B measurements can help in gonadal dysgenesis evaluation, androgen insensitivity management and also in the diagnosis of some gonadal tumors. In adult men, inhibin B evaluation is helpful in the investigation of male infertility, especially in the judgment of the prognosis of testicular biopsy in in-vitro fertilization programs. Although commercial kits for inhibin B measurement are available at present, its evaluation is accessible in the Czech Republic for the time being in only very limited number of laboratory centers.
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Authors | I Porsová-Dutoit |
Journal | Vnitrni lekarstvi
(Vnitr Lek)
Vol. 54
Issue 11
Pg. 1059-62
(Nov 2008)
ISSN: 0042-773X [Print] Czech Republic |
Vernacular Title | Význam stanovování inhibinu B v klinické andrologické praxi. |
PMID | 19069679
(Publication Type: English Abstract, Journal Article, Review)
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Chemical References |
- Biomarkers
- inhibin B
- Inhibins
|
Topics |
- Biomarkers
(blood)
- Gonadal Disorders
(diagnosis)
- Humans
- Inhibins
(blood)
- Male
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