Case report: failure of subcutaneous ivermectin in treating Strongyloides hyperinfection.

A man with Escherichia coli meningitis and bacteremia, while on dexamethasone, developed Strongyloides hyperinfection syndrome and died despite salvage therapy with subcutaneous ivermectin. We report the first documented total and free levels of subcutaneous ivermectin used for therapy.
AuthorsVictor Leung, Ghada N Al-Rawahi, Jennifer Grant, Lawrence Fleckenstein, William Bowie
JournalThe American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 79 Issue 6 Pg. 853-5 (Dec 2008) ISSN: 1476-1645 [Electronic] United States
PMID19052292 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiparasitic Agents
  • Ivermectin
  • Aged
  • Animals
  • Antiparasitic Agents (administration & dosage, therapeutic use)
  • Humans
  • Injections, Subcutaneous
  • Ivermectin (administration & dosage, therapeutic use)
  • Male
  • Strongyloides stercoralis
  • Strongyloidiasis (complications, drug therapy, parasitology)

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