| Abstract |
Chaetoglobins A (1) and B (2), two azaphilone alkaloid dimers with an unprecedented skeleton, were characterized from an endophytic fungus Chaetomium globosum with the former ascertained to be a significant cytotoxin valuable for anti- tumor drug discovery. |
| Authors | Hui Ming Ge, Wei Yun Zhang, Gang Ding, Patchareenart Saparpakorn, Yong Chun Song, Supa Hannongbua, Ren Xiang Tan |
| Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Issue 45
Pg. 5978-80
(Dec 07 2008)
ISSN: 1359-7345 [Print] England |
| PMID | 19030558
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
| Chemical References |
- Alkaloids
- Antineoplastic Agents
- Benzopyrans
- Isoquinolines
- Pigments, Biological
- azaphilone
- chaetoglobin A
- chaetoglobin B
|
| Topics |
- Alkaloids
(chemistry, isolation & purification, pharmacology)
- Antineoplastic Agents
(chemistry, isolation & purification, pharmacology)
- Benzopyrans
(chemistry, isolation & purification, pharmacology)
- Chaetomium
(chemistry)
- Drug Screening Assays, Antitumor
- Isoquinolines
(chemistry, pharmacology)
- Molecular Structure
- Pigments, Biological
(chemistry, isolation & purification, pharmacology)
- Tumor Cells, Cultured
|
