Halofantrine hydrochloride--efficacy and safety in children with acute malaria.

Abstract	Thirty two children with symptomatic malaria due to P. vivax and P. Falciparum infections were treated with three doses of Halofantrine hydrochloride 8 mg/kg body weight every 6 hours. Mean fever clearance was 30 hours (range 24-48 hours). No significant clinical or biochemical side effects were observed. Symptoms cleared rapidly. Halofantrine hydrochloride was found to be highly effective and appeared to have no side effects in children with acute malaria infections.
Authors	M A Khan, G N Rehman, S A Qazi
Journal	JPMA. The Journal of the Pakistan Medical Association (J Pak Med Assoc) Vol. 41 Issue 1 Pg. 8-10 (Jan 1991) ISSN: 0030-9982 [Print] Pakistan
PMID	1900550 (Publication Type: Journal Article)
Chemical References	Antimalarials Phenanthrenes halofantrine
Topics	Acute Disease Animals Antimalarials (administration & dosage, adverse effects, therapeutic use) Child Child, Preschool Female Humans Infant Malaria (drug therapy, parasitology) Male Phenanthrenes (administration & dosage, adverse effects, therapeutic use) Plasmodium falciparum Plasmodium vivax Safety

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