Solitary fibrous tumor of the liver expressing CD34 and vimentin: a case report.

Abstract

A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported. An 82-year-old female presented with left upper abdominal discomfort, a firm mass on palpation, and imaging studies revealed a large tumor, 15 cm in diameter, arising from the left lobe of the liver. A formal left hepatectomy was performed. Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma. Immunohistochemistry disclosed diffuse CD34 and positive vimentin, supporting the diagnosis of a benign SFT. The patient remained well 21 months after surgery. SFT of the liver is a very rare neoplasm of mesenchymal origin. In most cases it is a benign lesion, although some may have malignant histological features and recur locally or metastasize. With less than 30 reported cases in the literature, little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy. Complete surgical resection remains the cornerstone of its treatment.

• Authors: Dimitris-P Korkolis, Katerina Apostolaki, Chrysanthi Aggeli, George Plataniotis, Emmanuel Gontikakis, Dimitra Volanaki, Maria Sebastiadou, Dimitris Dimitroulopoulos, Dimitris Xinopoulos, George-N Zografos, Perikles-P Vassilopoulos
• Journal: World journal of gastroenterology (World J Gastroenterol) Vol. 14 Issue 40 Pg. 6261-4 (Oct 28 2008) ISSN: 1007-9327 [Print] United States
• PMID: 18985821 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antigens, CD34
• Vimentin

Topics

• Aged, 80 and over
• Antigens, CD34 (analysis)
• Female
• Hepatectomy
• Humans
• Immunohistochemistry
• Liver Neoplasms (chemistry, immunology, pathology, surgery)
• Magnetic Resonance Imaging
• Solitary Fibrous Tumors (chemistry, immunology, pathology, surgery)
• Treatment Outcome
• Vimentin (analysis)