Origin of so-called mesothelioma of the atrioventricular node. An immunohistochemical study.

Abstract

To determine the origin of a mesothelioma of the atrioventricular node, immunohistochemical studies that used various antibodies, including the antibody against mesothelial cells, were performed on a mesothelioma of the atrioventricular node in a case. The lining cells of the tubules that composed the tumor were negative when tested with anti-mesothelial cell antibodies. Carcinoembryonic antigen was negative, but the secretory component was positive. Serotonin and calcitonin were positive in a few cells. We concluded that a mesothelial origin was unlikely, and it was suggested that the tumor was of an entodermal origin.

• Authors: N Monma, R Satodate, A Tashiro, I Segawa
• Journal: Archives of pathology & laboratory medicine (Arch Pathol Lab Med) Vol. 115 Issue 10 Pg. 1026-9 (Oct 1991) ISSN: 0003-9985 [Print] United States
• PMID: 1898229 (Publication Type: Case Reports, Journal Article)

Topics

• Atrioventricular Node (metabolism, pathology, ultrastructure)
• Heart Neoplasms (metabolism, pathology, ultrastructure)
• Humans
• Immunohistochemistry
• Male
• Mesothelioma (metabolism, pathology, ultrastructure)
• Microscopy, Electron
• Middle Aged