Abstract | PURPOSE: METHODS: Twenty-five diabetic patients (19 male and 6 female, 64.7 +/- 10.2 yr), who were planning to undergo hyperbaric oxygen therapy for non-healing lower extremity ulcers, were prospectively enrolled into the study. All patients were evaluated with echocardiography before the study. Heart rate and arterial blood pressure of patients were measured, and venous blood samples were drawn from each patient for NT-proBNP analysis before and immediately after the hyperbaric oxygen therapy. RESULTS:
NT-proBNP levels increased from 815 +/- 1096 pg/ml to 915 +/- 1191 pg/ml after HBO2 therapy (P < 0.05). Heart rate and arterial blood pressure did not change with HBO2 therapy (P > 0.05). CONCLUSION:
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Authors | Senol Yildiz, Gunalp Uzun, Omer Uz, Osman Metin Ipcioglu, Ejder Kardesoglu, Omer Ozcan |
Journal | Clinical and investigative medicine. Medecine clinique et experimentale
(Clin Invest Med)
Vol. 31
Issue 5
Pg. E231-5
(Oct 01 2008)
ISSN: 1488-2353 [Electronic] Canada |
PMID | 18980711
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Biomarkers
- Peptide Fragments
- pro-brain natriuretic peptide (1-76)
- Natriuretic Peptide, Brain
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Topics |
- Aged
- Biomarkers
(blood)
- Diabetic Foot
(blood, therapy)
- Female
- Heart Ventricles
(metabolism)
- Humans
- Hyperbaric Oxygenation
- Male
- Middle Aged
- Myocardium
(metabolism)
- Natriuretic Peptide, Brain
(blood)
- Peptide Fragments
(blood)
- Prospective Studies
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