Dermabond tissue adhesive versus Steri-Strips in unilateral cleft lip repair: an audit of infection and hypertrophic scar rates.

Abstract

OBJECTIVE:

The purpose of this study was to compare the infection and hypertrophic scar rates in unilateral cleft lip repairs, having had Steri-Strips or Dermabond tissue glue applied across the repair as the final stage.

DESIGN:

Retrospective study over 13 years of 307 unilateral cleft lip repairs by a single surgeon. The application of either Steri-Strips from 1992 to 1998 (121 patients) or Dermabond tissue adhesive from 1998 to 2006 (186 patients) was used in the final stage of the repair.

SETTING:

Regional Centre for Cleft Lip and Palate Care, South West of England.

PARTICIPANTS:

307 consecutive unilateral cleft lip patients seen from 1992 to 2006.

MAIN OUTCOME MEASURES AND RESULTS:

There were five (4%) infections in the Steri-Strip group. All infections were with Staphylococcus aureus. No infections occurred in the Dermabond group (p< .001). There were 15 (12%) hypertrophic scars in the Steri-Strip group and 33 (18%) hypertrophic scars in the Dermabond group (p= .142). Revision surgery was required in a total of seven (6%) patients in the Steri-Strip group. No revisions were required in the Dermabond group (p. 1).

CONCLUSION:

We found a lower infection and revision rate and a similar hypertrophic scar rate when Dermabond was used instead of Steri-Strips in the final stage of unilateral cleft lip repair and suggest this study further supports the use of octyl-2-cyanoacrylate tissue adhesive in unilateral cleft lip repair.

• Authors: Andrew D H Wilson, Nigel Mercer
• Journal: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (Cleft Palate Craniofac J) Vol. 45 Issue 6 Pg. 614-9 (Nov 2008) ISSN: 1055-6656 [Print] United States
• PMID: 18956934 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Cyanoacrylates
• Tissue Adhesives
• octyl 2-cyanoacrylate

Topics

• Cleft Lip (surgery)
• Cyanoacrylates
• England
• Follow-Up Studies
• Humans
• Infant
• Keloid (etiology, prevention & control)
• Oral Surgical Procedures (adverse effects, methods)
• Plastic Surgery Procedures (adverse effects, methods)
• Reoperation
• Retrospective Studies
• Surgical Tape
• Surgical Wound Infection (etiology, prevention & control)
• Tissue Adhesives