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[A case of recurrent breast cancer with multiple lung metastases responding to anastrozole monotherapy].

Abstract
A 51-year-old postmenopausal woman was referred to our hospital for treatment of ER-positive recurrent breast cancer. The patient had lung and pleural metastases with pleural effusion from breast cancer. She was treated with anastrozole, a 3rd-generation aromatiase inhibitor. The efficacy of the treatment was definite: the multiple metastatic lung lesions showed a partial response after 5 months' treatment, and reached a complete response after 14 months' treatment. The patient experienced no adverse effects with this therapy. Anastrozole therapy is a useful treatment for postmenopausal woman with ER-positive recurrent breast cancer.
AuthorsShuichiro Maruyama, Maiko Ito, Yutaka Hirano, Toshiro Shimo, Shinsuke Hashida, Korechika Iga, Michio Inukai, Yoshiaki Kanaya, Nobuji Yokoyama
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 35 Issue 10 Pg. 1787-9 (Oct 2008) ISSN: 0385-0684 [Print] Japan
PMID18931590 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Biomarkers, Tumor
  • Nitriles
  • Triazoles
  • Anastrozole
Topics
  • Anastrozole
  • Biomarkers, Tumor (blood)
  • Breast Neoplasms (blood, drug therapy, pathology, surgery)
  • Female
  • Humans
  • Lung Neoplasms (blood, diagnostic imaging, drug therapy, secondary)
  • Middle Aged
  • Neoplasm Recurrence, Local (blood, diagnostic imaging, drug therapy)
  • Nitriles (therapeutic use)
  • Radiography
  • Triazoles (therapeutic use)

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