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Antibiotic treatment of rickettsiosis, recent advances and current concepts.

Abstract
The author reviews the recent advances in the treatment of Mediterranean Spotted Fever and Q fever. In mediterranean spotted fever (M.S.F.), in vitro and preliminary in vivo data support the place of quinolones and josamycin in the treatment of M.S.F. In children josamycin could become the first choice drug as well as in pregnant woman. In Q fever chronic disease should be treated using a combination of antibiotic (doxycycline + quinolones) for a minimum of 3 years.
AuthorsD Raoult
JournalEuropean journal of epidemiology (Eur J Epidemiol) Vol. 7 Issue 3 Pg. 276-81 (May 1991) ISSN: 0393-2990 [Print] Netherlands
PMID1884779 (Publication Type: Journal Article, Review)
Chemical References
  • 4-Quinolones
  • Anti-Infective Agents
  • Josamycin
  • Doxycycline
  • Rifampin
Topics
  • 4-Quinolones
  • Anti-Infective Agents (therapeutic use)
  • Boutonneuse Fever (drug therapy)
  • Chronic Disease
  • Coxiella
  • Doxycycline (therapeutic use)
  • Drug Therapy, Combination
  • Humans
  • Josamycin (therapeutic use)
  • Q Fever (drug therapy)
  • Recurrence
  • Rickettsia Infections (drug therapy)
  • Rifampin (therapeutic use)

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