Magnetic resonance imaging of hyperbaric oxygen treated rats with spinal cord injury: preliminary studies.

Abstract

Magnetic resonance imaging (MRI) has been performed to assess the efficacy of hyperbaric oxygen (HBO) treatment on experimental spinal cord injury in a rat animal model. A moderately severe injury, similar to Type III injury seen in humans (Kulkarni et al. Radiology 164:837;1987) has been chosen for these studies. An improvement in the neurologic recovery (based on Tarlov scale) has been observed following HBO treatment over a period of 72 hr. Based on MRI, HBO treatment appears to arrest the spread of hemorrhage and resolve edema.

• Authors: P A Narayana, W A Kudrle, S J Liu, J H Charnov, B D Butler, J H Harris Jr
• Journal: Magnetic resonance imaging (Magn Reson Imaging) Vol. 9 Issue 3 Pg. 423-8 ( 1991) ISSN: 0730-725X [Print] Netherlands
• PMID: 1881262 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Topics

• Animals
• Hyperbaric Oxygenation
• Magnetic Resonance Imaging
• Male
• Rats
• Rats, Inbred Strains
• Spinal Cord (pathology)
• Spinal Cord Injuries (diagnosis, pathology, therapy)