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Typhilitis in the pediatric patient.

Abstract
Cancer statistics in children are promising as mortality rates consistently decrease, reflecting newer chemotherapeutic agents and the evolution of hematopoietic stem cell transplant. Typhilitis or neutropenic enterocolitis is a potentially life-threatening complication of cancer treatment often found in immunocompromised children receiving vigorous chemotherapeutic regimens and noted in children post-stem-cell transplant. Recent literature suggests a relationship between typhilitis and other types of cancers and immunocompromised illness occurring in both children and adults. The pathogenesis of typhilitis is poorly understood, with limited evidence regarding incidence. Nursing care and assessment of children receiving oncologic treatment requires vigilance and immediate response to prevent and manage complications, especially gastrointestinally related typhilitis.
AuthorsCathy Haut
JournalJournal of infusion nursing : the official publication of the Infusion Nurses Society (J Infus Nurs) Vol. 31 Issue 5 Pg. 270-7 ( 2008) ISSN: 1539-0667 [Electronic] United States
PMID18806637 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antineoplastic Agents
Topics
  • Antineoplastic Agents (adverse effects, therapeutic use)
  • Child
  • Female
  • Humans
  • Leukemia, Myeloid, Acute (complications, drug therapy)
  • Typhlitis (complications, nursing, physiopathology, therapy)

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