Current treatment concepts for neuromas-in-continuity.

Abstract

SUMMARY:

A neuroma-in-continuity is a neuroma that results from failure of the regenerating nerve growth cone to reach peripheral targets. It occurs within an intact nerve in response to internally damaged fascicles, resulting in a distal portion of the nerve that no longer functions properly. Management of neuromas-in-continuity is challenging. Chemical methods, and microsurgical techniques including fascicular ligation, and burying into muscle and bone have been reported to prevent neuroma-in-continuity formation. The purpose of this article is to present novel techniques for neuroma-in-continuity management, and to discuss the related literature.

• Authors: Andreas F Mavrogenis, Kitty Pavlakis, Anna Stamatoukou, Panayiotis J Papagelopoulos, Stamatios Theoharis, Aristidis B Zoubos, Zijie Zhang, Panayotis N Soucacos
• Journal: Injury (Injury) Vol. 39 Suppl 3 Pg. S43-8 (Sep 2008) ISSN: 1879-0267 [Electronic] Netherlands
• PMID: 18715561 (Publication Type: Journal Article, Review)

Chemical References

• Immunotoxins
• Neurotoxins

Topics

• Animals
• Humans
• Immunotoxins (therapeutic use)
• Microsurgery (methods)
• Neuroma (etiology, therapy)
• Neurosurgical Procedures (methods)
• Neurotoxins (therapeutic use)
• Peripheral Nerve Injuries
• Peripheral Nervous System Neoplasms (etiology, therapy)