Abstract |
The majority of extramedullary plasmacytomas involve the upper respiratory tract but only a few are associated with serum monoclonal gammopathy. Most extramedullary plasmacytomas respond to local radiotherapy and have a better prognosis than multiple myeloma. Solitary plasmacytomas, involving the pleura, are very rare. This case report describes a patient with a solitary extramedullary plasmacytoma involving the pleura, and no evidence of serum, urine or pleural fluid paraproteins. Diagnosis was made by strongly positive immunohistochemical stains with CD38, CD138 and MUM-1 of the pleural tumour. The response to both radiotherapy and chemotherapy was poor and the patient died shortly after diagnosis.
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Authors | Po Hao Feng, Chung-Chi Huang, Chih-Wei Wang, Yao-Kuang Wu, Ying-Huang Tsai |
Journal | Respirology (Carlton, Vic.)
(Respirology)
Vol. 13
Issue 5
Pg. 751-3
(Sep 2008)
ISSN: 1440-1843 [Electronic] Australia |
PMID | 18713097
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
- Interferon Regulatory Factors
- Paraproteins
- Syndecan-1
- interferon regulatory factor-4
- ADP-ribosyl Cyclase 1
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Topics |
- ADP-ribosyl Cyclase 1
(metabolism)
- Adult
- Humans
- Interferon Regulatory Factors
(metabolism)
- Lung
(diagnostic imaging, metabolism)
- Male
- Paraproteinemias
(diagnosis, metabolism)
- Paraproteins
(metabolism)
- Plasmacytoma
(diagnosis, metabolism, therapy)
- Pleural Effusion, Malignant
(diagnosis, metabolism)
- Pleural Neoplasms
(diagnosis, metabolism, therapy)
- Radiography, Thoracic
- Syndecan-1
(metabolism)
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