Bovine pericardium in treating large corneal perforation secondary to alkali injury: a case report.

Abstract

To describe use of a locally processed bovine pericardium (BP) to cover a large central corneal perforation following alkali injury and discuss postoperative outcome. A 27-year-old Malay male patient presented two weeks after alkali splashed in his left eye while working. A clinical diagnosis of left central corneal ulcer with limbal ischemia following alkali injury with secondary infection was made. After failed medical therapy, we performed a Gunderson conjunctival flap under local anesthesia that retracted after one week and resulted in a large central corneal perforation with surrounding stromal thinning. The perforation was covered with a locally processed BP xenograft (Lyolemb) supplied by the National Tissue Bank, University Sains Malaysia. Nine months follow-up showed a well-taken graft without any exposure/dehiscence and minimal inflammation. Amniotic membrane transplantation when used as a patch graft needs an urgent tectonic graft to promote corneal stability in patients with severe corneal thinning. The use of processed BP can be a viable option in treating such cases.

• Authors: Rajesh K Khanna, Ezanee Mokhtar
• Journal: Indian journal of ophthalmology (Indian J Ophthalmol) 2008 Sep-Oct Vol. 56 Issue 5 Pg. 429-30 ISSN: 0301-4738 [Print] India
• PMID: 18711278 (Publication Type: Case Reports, Journal Article)

Chemical References

• Alkalies

Topics

• Adult
• Alkalies (adverse effects)
• Animals
• Burns, Chemical (etiology, pathology, surgery)
• Cattle
• Cornea (drug effects, surgery)
• Corneal Injuries
• Eye Burns (chemically induced, pathology, surgery)
• Follow-Up Studies
• Humans
• Male
• Ophthalmologic Surgical Procedures (methods)
• Pericardium (transplantation)
• Rupture
• Transplantation, Heterologous
• Trauma Severity Indices