Abstract | INTRODUCTION: 'Red Man Syndrome' is a recognized adverse reaction to intravenous vancomycin therapy. This case concerns an elderly woman who developed a 'Red Man Syndrome' reaction whilst on oral vancomycin therapy for Clostridium difficile (C difficile) diarrhoea. Isolated case reports exist recording this reaction in association with oral vancomycin therapy in patients with inflammatory bowel conditions or impaired renal function, of which this patient had both. CASE PRESENTATION: CONCLUSION: This case is important in the light of the increasing use of oral vancomycin to treat C. difficile diarrhoea, a rising problem in the UK. It also calls us to review our understanding of the mechanism of the 'Red Man Syndrome' reaction. It is possible that significant absorption of orally administered vancomycin occurs in the presence of an inflammatory bowel condition.
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Authors | Phillippa Bailey, Henry Gray |
Journal | Cases journal
(Cases J)
Vol. 1
Issue 1
Pg. 111
(Aug 18 2008)
ISSN: 1757-1626 [Electronic] England |
PMID | 18710566
(Publication Type: Journal Article)
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