Abstract | OBJECTIVE: METHODS: RESULTS: Preoperative plasma B-type natriuretic peptide concentration predicted ventricular dysfunction, hospital stay, and mortality in univariate and multivariable analyses. Logistic regression demonstrated preoperative B-type natriuretic peptide to independently predict ventricular dysfunction (odds ratio 1.92, 95% confidence interval 1.12-3.29, P = .018), after adjustment for preoperative left ventricular ejection fraction, congestive heart failure severity, and other clinical predictors. Multivariable Cox proportional hazards models showed preoperative B-type natriuretic peptide to independently predict hospital stay (hazard ratio 1.42, 95% confidence interval 1.18-1.72, P = .0002) and mortality (hazard ratio 1.89, 95% confidence interval 1.08-3.33, P = .026). CONCLUSION:
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Authors | Amanda A Fox, Stanton K Shernan, Charles D Collard, Kuang-Yu Liu, Sary F Aranki, Stacia M DeSantis, Petr Jarolim, Simon C Body |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 136
Issue 2
Pg. 452-61
(Aug 2008)
ISSN: 1097-685X [Electronic] United States |
PMID | 18692657
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers
- Cardiotonic Agents
- Natriuretic Peptide, Brain
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Assisted Circulation
- Biomarkers
(blood)
- Cardiotonic Agents
(therapeutic use)
- Coronary Artery Bypass
(adverse effects, mortality)
- Female
- Humans
- Length of Stay
- Male
- Middle Aged
- Natriuretic Peptide, Brain
(blood)
- Postoperative Care
- Postoperative Complications
- Survival Rate
- Ventricular Dysfunction
(diagnosis, etiology)
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