Abstract | BACKGROUND: CASE REPORT: A postmenopausal patient is described with the classical clinical signs of the myomatous erythrocytosis syndrome. During hysterectomy we demonstrated a large gradient between the erythropoietin levels in the uterine vein and artery, providing direct evidence for in vivo erythropoietin production by the myomatous uterus. CONCLUSION: While erythropoietin and its receptor are consecutively expressed in normal and myomatous uterine tissue, it is amazing that erythrocytosis occurs so rarely in such a frequent disorder as uterine myomatous. We strongly advocate cytogenetic examination of the myomatous tissue of subsequent patients with this entity.
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Authors | L T Vlasveld, C W M de Wit, R A Verweij, A Castel, P M Jansen, A A W Peters |
Journal | The Netherlands journal of medicine
(Neth J Med)
2008 Jul-Aug
Vol. 66
Issue 7
Pg. 283-5
ISSN: 0300-2977 [Print] Netherlands |
PMID | 18663256
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Diagnosis, Differential
- Erythropoietin
(blood)
- Female
- Follow-Up Studies
- Humans
- Immunohistochemistry
- Leiomyoma
(blood, diagnosis)
- Middle Aged
- Polycythemia
(blood, diagnosis)
- Syndrome
- Uterine Neoplasms
(blood, diagnosis)
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