Ciprofloxacin: drug of choice in the treatment of malignant external otitis (MEO).

Abstract

Ciprofloxacin, a fluorinated quinolone with high efficacy against Pseudomonas aeruginosa, was used in the treatment of 10 consecutive patients with malignant external otitis. All patients had skull base osteomyelitis documented by nuclear and computed tomography (CT) scans. Dosages of 1.5 g of ciprofloxacin daily were used for a mean average of 10 weeks. All patients were considered cured with a minimum follow-up of 18 months after completion of therapy. A new classification of malignant external otitis (MEO) is presented.

• Authors: M J Levenson, S C Parisier, J Dolitsky, G Bindra
• Journal: The Laryngoscope (Laryngoscope) Vol. 101 Issue 8 Pg. 821-4 (Aug 1991) ISSN: 0023-852X [Print] United States
• PMID: 1865729 (Publication Type: Journal Article)

Chemical References

• Ciprofloxacin

Topics

• Aged
• Aged, 80 and over
• Chronic Disease
• Ciprofloxacin (therapeutic use)
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Osteomyelitis (complications, drug therapy, microbiology)
• Otitis Externa (diagnosis, drug therapy, etiology)
• Pseudomonas Infections (diagnosis, drug therapy)
• Tomography, X-Ray Computed