Abstract |
Although most patients with colonic diverticula have no symptoms, perforation or bleeding can be troublesome. Recently, we treated an elderly patient with a diverticular perforation of the sigmoid colon who required a loop colostomy and later resection of the diseased colon. Between the operations, the colostomy resembled a sea slug with horns, which represented eversions of the diverticula. This interesting phenomenon suggests that diverticula may be everted as pseudopolyps and ligated endoscopically. Therefore, the procedure was tested on a Landrace pig, of which the large bowel wall was pulled with an endoscope at 9 different sites using forceps (n=6) or suction (n=3) and ligated. Four days later, reexamination revealed total necrosis at 8 sites and ulceration at 1. The animal was well. The bowel removed 2 weeks later showed mucosal fold convergences without perforations. Our procedure can be used for prophylactic or therapeutic treatment of patients with colonic diverticula.
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Authors | Koho Akimaru, Hideyuki Suzuki, Hiroyuki Tsuruta, Yoshinori Ishikawa, Takashi Tajiri, Tetsuya Horikita |
Journal | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
(J Nippon Med Sch)
Vol. 75
Issue 3
Pg. 157-61
(Jun 2008)
ISSN: 1345-4676 [Print] Japan |
PMID | 18648173
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged, 80 and over
- Animals
- Colon, Sigmoid
(surgery)
- Colonoscopy
(methods)
- Colostomy
- Diverticulum, Colon
(surgery)
- Female
- Humans
- Ligation
(methods)
- Swine
- Treatment Outcome
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