[Dermatopathy associated with levamisole-induced reversible posterior leukoencephalopathy].

Abstract

Levamisole is an antihelmintic drug that stimulates antibodies formation increasing both T response, and neutrophilic response, and quimiotaxis. It is used in dermatology for the treatment of plane warts, erythema multiforme, aphtous ulcers and, with prednisone, in lichen planus. With prolonged use this drug has been implicated in adverse dermatological reactions as lichenoid eruptions, ulcers and vasculitis. We present a 9-years old girl who developed a cutaneous eruption and a reverse leucoencephalopathy with a short treatment but high doses of the drug.

• Authors: María Del C Boente, Hilda Bibas Bonet, Norma B Primc
• Journal: Archivos argentinos de pediatria (Arch Argent Pediatr) Vol. 106 Issue 1 Pg. 42-6 (Feb 2008) ISSN: 1668-3501 [Electronic] Argentina
• Vernacular Title: Dermatopatía asociada a leucoencefalopatía posterior reversible inducida por levamisol.
• PMID: 18636134 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Levamisole

Topics

• Child
• Drug Eruptions (complications, etiology)
• Female
• Humans
• Levamisole (adverse effects)
• Posterior Leukoencephalopathy Syndrome (chemically induced, complications)
• Skin Diseases (drug therapy)
• Warts (drug therapy)