In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.

Abstract

This study evaluated the in vitro activity of ceftaroline, a novel cephalosporin with broad-spectrum activity against gram-negative and -positive pathogens, against 4,151 recent clinical isolates collected in the United States. Ceftaroline was very potent against bacteria found in community- and hospital-acquired infections, including methicillin-resistant Staphylococcus aureus, multidrug-resistant Streptococcus pneumoniae, and common Enterobacteriaceae spp.

• Authors: Yigong Ge, Donald Biek, George H Talbot, Daniel F Sahm
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 52 Issue 9 Pg. 3398-407 (Sep 2008) ISSN: 1098-6596 [Electronic] United States
• PMID: 18625769 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Cephalosporins
• T 91825

Topics

• Anti-Bacterial Agents (pharmacology)
• Cephalosporins (pharmacology)
• Drug Resistance, Multiple, Bacterial
• Gram-Negative Bacteria (drug effects, isolation & purification)
• Gram-Positive Bacteria (drug effects, isolation & purification)
• Humans
• Microbial Sensitivity Tests
• United States