Abstract | OBJECTIVE: Although surgery is the first choice of therapy for plunging ranula, it is associated with technical difficulties, morbidity and recurrence. Plunging ranula may be also primarily treated with nonsurgical sclerotherapy, but there is little experience in pediatric patients. We, therefore, assessed the efficacy of OK-432 sclerotherapy for pediatric plunging ranula. METHODS: RESULTS: Total or nearly total shrinkage was observed in 6 of 9 patients; marked reduction (>50% of original size) in 2; and partial reduction (<50% of original size) in 1. At a mean follow-up of 26 months after last sclerotherapy, recurrence was observed in only 1 patient; this patient showed complete response after reinjection of OK-432 solution. No significant complications were observed, with only fever and mild local pain observed in 4 patients for 2-4 days after treatment. CONCLUSIONS:
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Authors | Jong-Lyel Roh, Hyo Sun Kim |
Journal | International journal of pediatric otorhinolaryngology
(Int J Pediatr Otorhinolaryngol)
Vol. 72
Issue 9
Pg. 1405-10
(Sep 2008)
ISSN: 0165-5876 [Print] Ireland |
PMID | 18617276
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Antineoplastic Agents
- Picibanil
|
Topics |
- Adolescent
- Antineoplastic Agents
(administration & dosage, therapeutic use)
- Child
- Child, Preschool
- Female
- Humans
- Male
- Picibanil
(administration & dosage, therapeutic use)
- Prospective Studies
- Punctures
- Ranula
(therapy)
- Sclerotherapy
(methods)
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