Endometrial leimyosarcoma is rare
neoplasm of all the uterine
malignancies. We herein present a case of metastatic pulmonary
tumor derived from endometrial
leiomyosarcoma She had undergone
hysterectomy for
leiomyosarcoma. About 10 years after the
hysterectomy, metastatic hepatic
tumors and peritoneal dissemination were pointed out. Following
chemotherapy of
cisplatin, ifomide and pirarubicine, right
hepatectomy was performed. About 12 years after the
hysterectomy, a metastatic lesion appeared in the right lower lung field and right S6
segmentectomy was performed. About 15 months after the pulmonary resection, another metastatic lesion appeared in the remaining right lower lobe. The mass grew so rapidly with involvement to adjacent organs that pericardial resection was necessary with completion right lower lobectomy. Postoperative
chemotherapy was performed with the same regimen as previously performed. About 10 months after the second pulmonary resection, she died due to dissemination in the right haemithorax and malignant
pericardial effusion. Careful follow up after the surgery for the uterine
leiomyosarcoma is recommended because metastatic
leiomyosarcoma possibly appears even after a long interval, and its progress can be so intensive that
adjuvant chemotherapy is necessary if it can not be treated surgically alone.