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Arsenic poisoning in livestock.

Abstract
Arsenic is an important heavy metal intoxicant to livestock. Arsenical pesticides present significant hazards to animal health. The toxicity of arsenic varies with several factors--its chemical form, oxidation states, solubility. The phenylarsonic compounds are the least toxic and are used as feed additives in swine and poultry rations. However, roxarsone has a higher absolute toxicity than arsanilic acid. The mechanism of action is related to its reaction with sulfhydryl groups values to enzyme function and to its ability to uncouple oxydative phosphorylation. Most animals excrete arsenic quite readily. Toxicoses caused by inorganic and aliphatic organic arsenicals result in a different clinical syndrome than that from the phenylarsonic compounds. Arsenic poisoning may be confused with other types of intoxication. The specific antidote for inorganic arsenical poisoning is dimercaprol (BAL).
AuthorsL el Bahri, S Ben Romdane
JournalVeterinary and human toxicology (Vet Hum Toxicol) Vol. 33 Issue 3 Pg. 259-64 (Jun 1991) ISSN: 0145-6296 [Print] UNITED STATES
PMID1858306 (Publication Type: Journal Article)
Chemical References
  • Arsenicals
  • Arsenic
Topics
  • Animals
  • Animals, Domestic
  • Arsenic (chemistry, classification, pharmacokinetics)
  • Arsenic Poisoning
  • Arsenicals (adverse effects, classification)
  • Capillaries (drug effects)
  • Intestines (drug effects)
  • Oxidative Phosphorylation
  • Rumen (drug effects)

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