Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.

Abstract

The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through blood smear examination. These animals were divided into two groups i.e. A and B. Horses of Group A, were treated with diminazene diaceturate, while horses of Group B were treated with diminazene aceturate. Efficacy of the drugs was determined by the reversal of clinical signs and a negative blood smear examination. The efficacy of diminazene diaceturate was demonstrated to be 80% while diminazene aceturate was found to have 90% efficacy against babesiosis.

• Authors: Hamad Bin Rashid, Mamoona Chaudhry, Haroon Rashid, Khalid Pervez, Muhammad Arif Khan, Asim Khalid Mahmood
• Journal: Tropical animal health and production (Trop Anim Health Prod) Vol. 40 Issue 6 Pg. 463-7 (Aug 2008) ISSN: 0049-4747 [Print] United States
• PMID: 18575975 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Antiprotozoal Agents
• diminazene aceturate
• Diminazene

Topics

• Animals
• Antiprotozoal Agents (therapeutic use)
• Babesia (growth & development)
• Babesiosis (drug therapy, parasitology, veterinary)
• Diminazene (analogs & derivatives, therapeutic use)
• Female
• Horse Diseases (drug therapy, parasitology)
• Horses
• Male