Abstract | OBJECTIVES: METHODS: The clinical and laboratory records of 28 spontaneous pregnancies in six Bedouin women with CDA I were reviewed. The results were compared with findings from a retrospective review of a large population-based registry including all pregnancies in Bedouin women during the same 15-yr period. RESULTS: Eighteen pregnancies in women with CDA I (64%) were complicated. One pregnancy was aborted spontaneously in the first trimester and one resulted in a non-viable fetus (stillborn at 26 wk). Cesarean section (CS) was performed in 10 pregnancies (36%). Eleven of the 26 newborns (42%) had a LBW: six were born prematurely and five were small for gestational age. The odds ratio for CS in women with CDA I compared with healthy Bedouin women was 4.5 [95% confidence interval (CI) 1.2-10.3], and for a LBW infant, 5.5 (95% CI 2.4-12.3). Careful follow-up was associated with significantly better fetal outcome (P = 0.05). CONCLUSIONS: Pregnancies in women with CDA I are at high risk for delivery-related and outcome complications. To improve fetal outcome, women with CDA I should be carefully monitored during pregnancy.
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Authors | Hanna Shalev, Galit Perez Avraham, Reli Hershkovitz, Amalia Levy, Eyal Sheiner, Itai Levi, Hannah Tamary |
Journal | European journal of haematology
(Eur J Haematol)
Vol. 81
Issue 4
Pg. 317-21
(Oct 2008)
ISSN: 1600-0609 [Electronic] England |
PMID | 18573172
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Anemia, Dyserythropoietic, Congenital
- Female
- Humans
- Monitoring, Physiologic
- Pregnancy
- Pregnancy Complications
- Pregnancy Outcome
- Retrospective Studies
- Risk Factors
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