Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor.

Abstract

OBJECTIVE:

To present a case demonstrating lack of efficacy of an aromatase inhibitor in treating ureteral endometriosis.

DESIGN:

Case report.

SETTING:

A tertiary-care hospital.

PATIENT(S):

A 47-year-old woman with severe ureteral endometriosis.

INTERVENTION(S):

Anastrozole 1 mg daily for 15 months.

MAIN OUTCOME MEASURE(S):

Renal function.

RESULT(S):

Despite medical management with anastrozole, our patient continued to have worsening renal function and subsequently required surgical intervention.

CONCLUSION(S):

Anastrozole was ineffective at preventing deterioration of renal function in this patient.

• Authors: Justin Bohrer, Chi Chiung Grace Chen, Tommaso Falcone
• Journal: Fertility and sterility (Fertil Steril) Vol. 90 Issue 5 Pg. 2004.e7-9 (Nov 2008) ISSN: 1556-5653 [Electronic] United States
• PMID: 18555228 (Publication Type: Case Reports, Journal Article)

Chemical References

• Aromatase Inhibitors
• Nitriles
• Triazoles
• Anastrozole

Topics

• Anastrozole
• Aromatase Inhibitors (therapeutic use)
• Disease Progression
• Endometriosis (complications, drug therapy, physiopathology, surgery)
• Female
• Humans
• Kidney Function Tests
• Middle Aged
• Nitriles (therapeutic use)
• Severity of Illness Index
• Stents
• Treatment Failure
• Triazoles (therapeutic use)
• Ureteral Diseases (complications, drug therapy, physiopathology, surgery)
• Ureteral Obstruction (etiology, physiopathology, surgery)
• Urologic Surgical Procedures (instrumentation)