Hydroxocobalamin for poisoning caused by ingestion of potassium cyanide: a case study.

Abstract

Hydroxocobalamin, a precursor of vitamin B12, has a history of use in the prehospital setting in France for cyanide poisoning, particularly that associated with smoke inhalation. Because cyanide poisoning by ingestion is less common than smoke inhalation-associated cyanide poisoning, less information is available on prehospital use of hydroxocobalamin to treat cyanide poisoning by ingestion. This report describes a case of prehospital use of hydroxocobalamin for poisoning by ingestion of cyanide. The case supports the efficacy of hydroxocobalamin for acute cyanide poisoning caused by ingestion of a cyanide salt. No adverse events attributed to hydroxocobalamin were observed.

• Authors: Jean-Luc Fortin, Stanislas Waroux, J P Giocanti, Gilles Capellier, Michel Ruttimann, Jean-Jacques Kowalski
• Journal: The Journal of emergency medicine (J Emerg Med) Vol. 39 Issue 3 Pg. 320-4 (Sep 2010) ISSN: 0736-4679 [Print] United States
• PMID: 18554843 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2010. Published by Elsevier Inc.

Chemical References

• Antidotes
• Vitamin B Complex
• Potassium Cyanide
• Hydroxocobalamin

Topics

• Antidotes (therapeutic use)
• Humans
• Hydroxocobalamin (therapeutic use)
• Male
• Middle Aged
• Potassium Cyanide (poisoning)
• Suicide, Attempted
• Vitamin B Complex (therapeutic use)