Abstract |
Acute non lymphocytic leukemia ( AnLL) is the most common second malignancy (SM) in survivors of childhood Hodgkin's Disease (HD). Chemotherapy responsiveness is usually poor and death ensues briefly after diagnosis. We report the case of a 13 year-old girl, affected by HD, stage IV, mixed cellularity, who developed AnLL one year after the HD treatment was stopped. Autologous Bone Marrow Transplantation (ABMT) was performed 9 months after complete remission (CR) was achieved by chemotherapy. Presently, the patient is alive and on continues CR, 3 years and 7 months after ABMT. ABMT may be a promising approach for secondary AnLL, the prognosis of which is almost invariably fatal with conventional chemotherapy.
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Authors | F Rossetti, C Messina, P Colleselli, G De Silvestro, G Sotti, R Destro, L Zanesco |
Journal | Bone marrow transplantation
(Bone Marrow Transplant)
Vol. 7 Suppl 3
Pg. 131-2
( 1991)
ISSN: 0268-3369 [Print] England |
PMID | 1855076
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adolescent
- Bone Marrow Transplantation
(methods)
- Female
- Hodgkin Disease
(complications, pathology)
- Humans
- Leukemia, Monocytic, Acute
(etiology, pathology, surgery)
- Transplantation, Autologous
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