Abstract | BACKGROUND: OBJECTIVES: To assess the efficiency of and satisfaction with Singulair in asthmatic children under real-life conditions. METHODS:
Montelukast was prescribed for 6 weeks to a cohort of 506 children aged 2 to 18 years with mild to moderate persistent asthma, who were enrolled by 200 primary care pediatricians countrywide. Four clinical correlates of childhood asthma--wheeze, cough, difficulty in breathing, night awakening--were evaluated from patients' diary cards. RESULTS: Due to under-treatment by their physicians, almost 60% of the children were not receiving controller therapy at baseline. By the end of the study, which consisted of montelukast treatment, a significant improvement over baseline was noted in asthma symptoms and severity, as well as in treatment compliance. The participating pediatricians and parents were highly satisfied with the treatment. CONCLUSIONS: The results of this extensive study show that the use of montelukast as monotherapy in children presenting with persistent asthma resulted in a highly satisfactory outcome for themselves, their parents and their physicians.
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Authors | Israel Amirav |
Journal | The Israel Medical Association journal : IMAJ
(Isr Med Assoc J)
Vol. 10
Issue 4
Pg. 287-91
(Apr 2008)
ISSN: 1565-1088 [Print] Israel |
PMID | 18548983
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Acetates
- Anti-Asthmatic Agents
- Cyclopropanes
- Leukotriene Antagonists
- Quinolines
- Sulfides
- montelukast
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Topics |
- Acetates
(therapeutic use)
- Adolescent
- Anti-Asthmatic Agents
(therapeutic use)
- Asthma
(classification, drug therapy, physiopathology)
- Child
- Child, Preschool
- Cyclopropanes
- Female
- Humans
- Leukotriene Antagonists
(therapeutic use)
- Male
- Patient Satisfaction
- Quinolines
(therapeutic use)
- Severity of Illness Index
- Sulfides
- Treatment Outcome
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