Cis-platinum chemotherapy for ocular basal cell carcinoma.

Abstract

We have used intravenous cis-platinum chemotherapy in the treatment of three patients with basal cell carcinoma of the lid extending into the orbit. Cis-platinum chemotherapy caused a reduction in tumour size and thereby delayed surgery in all cases. It allowed for local resection in one case, appeared to delay a patient's exenteration in a second case, and was used prior to radiotherapy in a third case. While not curative, cis-platinum may be useful as an adjuvant to decrease tumour mass prior to local excision and for patients who refuse or must delay exenteration.

• Authors: M Morley, P T Finger, M Perlin, L R Weiselberg, D S DeBlasio
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 75 Issue 7 Pg. 407-10 (Jul 1991) ISSN: 0007-1161 [Print] England
• PMID: 1854693 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cisplatin

Topics

• Aged
• Aged, 80 and over
• Carcinoma, Basal Cell (diagnostic imaging, drug therapy, pathology)
• Cisplatin (administration & dosage, therapeutic use)
• Eyelid Neoplasms (drug therapy, pathology)
• Female
• Humans
• Infusions, Intravenous
• Male
• Neoplasm Invasiveness
• Orbit (diagnostic imaging)
• Orbital Neoplasms (diagnostic imaging, drug therapy)
• Tomography, X-Ray Computed