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Sheehan's syndrome associated with Glanzmann's Thrombasthenia: case report and literature review.

AbstractOBJECTIVES:
We aimed to present a case of Sheehan's syndrome associated with Glanzmann's thrombasthenia.
CASE REPORT:
A 41-year-old-woman presented with hemorrhagic diathesis needed blood transfusions occasionally during her life-time. In the course of her second delivery, four units of whole blood transfusion were required to control profuse uterine bleeding and her hemodynamic status. During postpartum period, she was not able to lactate and her menstrual periods did not return. Her hormonal profile revealed gonadotropin, TSH and prolactin deficiencies.
CONCLUSION:
According to our knowledge, this is the first case report of hypopituitarism developed after delivery in association with Glanzmann's thromboasthenia-induced severe uterine hemorrhage.
AuthorsT Bayraktaroglu, N Colak, M Nalcaci, M N Yenerel
JournalExperimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (Exp Clin Endocrinol Diabetes) Vol. 116 Issue 9 Pg. 549-53 (Oct 2008) ISSN: 0947-7349 [Print] Germany
PMID18523914 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Thyroid Hormones
  • Human Growth Hormone
  • Insulin-Like Growth Factor I
  • Hydrocortisone
Topics
  • Adult
  • Amenorrhea (etiology)
  • Blood Transfusion
  • Female
  • Flow Cytometry
  • Hemorrhagic Disorders (etiology, therapy)
  • Human Growth Hormone (blood)
  • Humans
  • Hydrocortisone (blood)
  • Hypopituitarism (complications)
  • Insulin-Like Growth Factor I (metabolism)
  • Pregnancy
  • Thrombasthenia (complications)
  • Thyroid Hormones (blood)

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