Bispectral index monitoring documents burst suppression during pentobarbital coma.

Abstract

During pentobarbital coma, electroencephalographic monitoring is used to document burst suppression (3-5 episodes of electrical activity/min). The current study evaluates the association of the bispectral index number and suppression ratio with a burst suppression pattern on electroencephalograph. The records of 7 patients (aged 2.9-14 years) who received pentobarbital for elevated intracranial pressure were retrospectively reviewed. The bispectral index number was 7 +/- 5, 14 +/- 3, and 37 +/- 12, whereas the suppression ratio was 93 +/- 7%, 75 +/- 6%, and 29 +/- 18% when the electroencephalograph showed <or= 2, 3-5, and >or= 6 bursts/min, respectively. The sensitivity and specificity of a bispectral index value of 10 to 20 were 96% and 92%, respectively, whereas the sensitivity and specificity of a suppression ratio of 65% to 85% were 89% and 88%, respectively, in demonstrating the presence of 3 to 5 bursts/min. Bispectral index monitoring may be easier to perform and may require less technical expertise to interpret.

• Authors: Joseph D Tobias
• Journal: Journal of intensive care medicine (J Intensive Care Med) 2008 Jul-Aug Vol. 23 Issue 4 Pg. 258-62 ISSN: 0885-0666 [Print] United States
• PMID: 18508838 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Pentobarbital

Topics

• Adolescent
• Child
• Child, Preschool
• Coma (chemically induced)
• Electroencephalography
• Female
• Humans
• Intracranial Pressure
• Male
• Monitoring, Physiologic
• Pentobarbital
• Sensitivity and Specificity