Abstract | BACKGROUND: Recent approaches to emergency treatment of eye burns have given rise to many questions on the effectiveness of traditional rinsing solutions. This led us to study the use of isotonic saline solution and a recently introduced, highly effective solution, Cederroth Eye Wash, in the initial treatment of eye burns. METHODS: A central area (Ø 10mm) of the cornea of isolated ex vivo rabbit eyes was burnt for 20s with 25+/-1.4 micro L of 2N NaOH. The anterior chamber pH was measured continuously via microelectrode. The corneas were immediately rinsed for 15 min with flow rates of 50, 100, 200, 300, 400, and 500 mL/min. RESULTS: After 20 min measurement, no significant differences in intraocular pH were found between unrinsed eyes and eyes rinsed with isotonic saline solution at any flow rate. At all flow rates, Cederroth Eye Wash brought about a significant decrease (p<0.001; Tukey t-test). CONCLUSIONS:
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Authors | Safwan Rihawi, Markus Frentz, Martin Reim, Norbert Franz Schrage |
Journal | Burns : journal of the International Society for Burn Injuries
(Burns)
Vol. 34
Issue 7
Pg. 1027-32
(Nov 2008)
ISSN: 1879-1409 [Electronic] Netherlands |
PMID | 18485603
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Hydroxides
- Isotonic Solutions
- Ophthalmic Solutions
- Sodium Chloride
- hydroxide ion
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Topics |
- Animals
- Burns, Chemical
(therapy)
- Eye Burns
(therapy)
- Hydrogen-Ion Concentration
- Hydroxides
(metabolism)
- Isotonic Solutions
(adverse effects)
- Models, Animal
- Ophthalmic Solutions
- Rabbits
- Sodium Chloride
(adverse effects)
- Treatment Failure
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