Controlling the clonal spread of Pseudomonas aeruginosa infection.

Abstract

To evaluate nosocomial infections due to imipenem-resistant and imipenem-susceptible Pseudomonas aeruginosa, a case-control study that included genotyping was performed. Hospitalization for more than 15 days was independently associated with infection with an imipenem-resistant organism. Sixty-seven percent of the imipenem-resistant isolates analyzed and 23% of the imipenem-susceptible isolates analyzed belonged to a single clone. Intervention led to a decrease in the number of infections due to imipenem-resistant and imipenem-susceptible P. aeruginosa.

• Authors: Graziella H Pereira, Anna S Levin, Helenice Bosco Oliveira, Maria Luiza Moretti
• Journal: Infection control and hospital epidemiology (Infect Control Hosp Epidemiol) Vol. 29 Issue 6 Pg. 549-52 (Jun 2008) ISSN: 0899-823X [Print] United States
• PMID: 18476775 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Imipenem

Topics

• Anti-Bacterial Agents (pharmacology)
• Case-Control Studies
• Cross Infection (epidemiology, microbiology, prevention & control)
• Drug Resistance, Bacterial (genetics)
• Female
• Genotype
• Humans
• Imipenem (pharmacology)
• Infection Control (methods)
• Length of Stay
• Male
• Middle Aged
• Pseudomonas Infections (epidemiology, microbiology, prevention & control)
• Pseudomonas aeruginosa (classification, drug effects, genetics)
• Risk Factors